SCHEMBL17607334

SCHEMBL17607334

Cc1ccc(N)c(O[PH](=O)Oc2cc(C)ccc2N)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALOX15 P16050 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
THRB P10828 1/20 0.46
ALDH1A1 P00352 6/20 0.44
TSHR P16473 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
ACHE P22303 1/20 0.39
HSD17B10 Q99714 2/20 0.38
GAA P10253 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8623181 0.79 HTT (0.46) TDP1SMN1; SMN2ALDH1A1TSHRCA1
SCHEMBL10978790 0.75 L3MBTL1 (0.41) CYP3A4TDP1SMN1; SMN2TP53ALDH1A1
SCHEMBL91459 0.74 ALDH1A1 (0.68) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL30294328 0.74 ALDH1A1 (0.68) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL29130888 0.72 CYP3A4 (0.52) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL14493632 0.72 CYP3A4 (0.52) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL20214357 0.71 TDP1 (0.50) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL31268447 0.71 LMNA (0.52) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL14872751 0.71 CA1 (0.56) CYP3A4TDP1ALOX15SMN1; SMN2TP53
SCHEMBL28471043 0.71 CYP3A4 (0.45) CYP3A4TDP1ALOX15SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120129825-A Methods, compositions and systems for assessing the quality of biological samples 10X基因组学有限公司 2025-06-10 CN disclosed
CN-115916972-A Compositions and methods for immobilized samples 10X基因组学有限公司 2023-04-04 CN disclosed
US-20170283860-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF ALDEHYDE ADDUCTS AND CROSSLINKS FROM BIOMOLECULES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2017-10-05 US disclosed
WO-2016044313-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF ALDEHYDE ADDUCTS AND CROSSLINKS FROM BIOMOLECULES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2016-03-24 WO disclosed