SCHEMBL8623181

SCHEMBL8623181

Cc1ccc(C)c(O[PH](=O)Oc2cc(C)ccc2C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 2/20 0.44
CYP2C9 P11712 2/20 0.42
ACHE P22303 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
TDP1 Q9NUW8 3/20 0.39
TTR P02766 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C8 P10632 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
PPARG P37231 1/20 0.39
HTR2B P41595 1/20 0.39
PPARA Q07869 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
CISD1 Q9NZ45 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759862 0.83 HTT (0.47) HTTLMNATSHRCYP2C9ACHE
SCHEMBL10978790 0.83 L3MBTL1 (0.41) LMNATSHRACHESMN1; SMN2TDP1
SCHEMBL987477 0.80 HTT (0.41) HTTLMNATSHRCYP2C9ACHE
SCHEMBL17607334 0.79 CYP3A4 (0.46) TSHRACHESMN1; SMN2TDP1GAA
SCHEMBL8626118 0.76 PKM (0.46) HTTLMNASMN1; SMN2CYP1A2ALDH1A1
SCHEMBL10977735 0.75 GRIN2D (0.32) TSHR
SCHEMBL3278966 0.74 ACHE (0.50) HTTLMNATSHRCYP2C9ACHE
SCHEMBL8620685 0.74 HSD17B10 (0.36) HTTLMNATSHRACHESMN1; SMN2
SCHEMBL3281430 0.73 TSHR (0.43) TSHRACHESMN1; SMN2CYP1A2ALDH1A1
SCHEMBL92174 0.72 ACHE (0.68) HTTLMNATSHRCYP2C9ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847199-A Derivative of phosphonic acid and process for the preparation thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-08 US claimed
EP-0842940-A1 Derivative of phosphonic acid and process for the preparation thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1998-05-20 EP claimed
JP-10195087-A None JP disclosed
US-5847199-A Derivative of phosphonic acid and process for the preparation thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-08 US disclosed
JP-H10195087-A PHOSPHONIC ACID DERIVATIVE AND ITS PRODUCTION NISSAN CHEM IND LTD 1998-07-28 JP disclosed
EP-0842940-A1 Derivative of phosphonic acid and process for the preparation thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1998-05-20 EP disclosed
EP-0038183-B1 POLYPHENYLENE ETHER RESIN COMPOSITIONS AND SHAPED ARTICLES THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-07-31 EP disclosed
US-4383066-A Polyphenylene ether resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-05-10 US disclosed
EP-0038183-A1 Polyphenylene ether resin compositions and shaped articles thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1981-10-21 EP disclosed