Sugi Predict

Sugi Predict / Compounds / SCHEMBL176085

SCHEMBL176085

SCHEMBL176085

CC#Cc1ccc(-c2ccccc2NC(=O)c2c(C)nn(C)c2F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ HTT P42858 3/20 0.40
▸ TSHR P16473 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ USP2 O75604 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.37
▸ TNF P01375 1/20 0.37
▸ IL2 P60568 1/20 0.37
▸ STIM1 Q13586 1/20 0.37
▸ ORAI1 Q96D31 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ NR3C1 P04150 2/20 0.36
▸ KDM4C Q9H3R0 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419113 1.00 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL29419108 0.89 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL121221 0.89 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL29419120 0.88 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL121859 0.88 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL29469568 0.88 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL231831 0.88 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL21638789 0.88 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL13455819 0.87 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL11930691 0.87 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 913 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 — — CN claimed
CN-108184905-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-12-28 — — CN claimed
CN-109169661-B Compositions comprising biological control agents and insecticides 拜耳作物科学股份公司 2021-09-21 — — CN claimed
CN-107926985-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-02-02 — — CN claimed
EP-3488700-B1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE BAYER CROPSCIENCE AG (DE) 2020-12-16 — — EP claimed
EP-2854545-B1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2020-10-21 — — EP claimed
CN-106962403-B Compositions comprising biological control agents and pesticides 拜耳作物科学股份公司 2020-05-05 — — CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 — — EP claimed
EP-2854532-B1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2019-08-07 — — EP claimed
EP-3488700-A1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE Bayer CropScience Aktiengesellschaft (DE) 2019-05-29 — — EP claimed
WO-2012076470-A1 PESTICIDAL MIXTURES WITH IMPROVED PROPERTIES BAYER CROPSCIENCE AG (DE) 2012-06-14 — — WO claimed
US-20120010073-A1 Anthranilamides in combination with fungicides BAYER CROPSCIENCE AG (DE) 2012-01-12 — — US claimed
WO-2011080044-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-07-07 — — WO claimed
US-20110124501-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-26 — — US claimed
US-20110064827-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-03-17 — — US claimed
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 — — US claimed
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 — — US claimed
US-20110003689-A1 USE OF POLYMERIC GUANIDINE DERIVATIVES FOR THE CONTROL OF UNWANTED MICROORGANISMS IN CROP PROTECTION AKA TECHNOLOGY GMBH (AT) 2011-01-06 — — US claimed
EP-2014166-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 — — EP claimed
EP-1982717-A1 Use of fungicides for treating fish mycoses Bayer CropScience AG (DE) 2008-10-22 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003689-A1 USE OF POLYMERIC GUANIDINE DERIVATIVES FOR THE CONTROL OF UNWANTED MICROORGANISMS IN CROP PROTECTION GDA, GMPS, GANC ALDH1A1 1741/4885MEN1 4049/4885KMT2A 1945/4885
US-20110064827-A1 Active compound combinations TST, DPM1, DDT ALDH1A1 1023/4885MEN1 1599/4885KMT2A 2698/4885
US-20110124501-A1 Active compound combinations CYP51A1, CA4, BROX ALDH1A1 240/4885MEN1 1526/4885KMT2A 3240/4885
US-20120010073-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 ALDH1A1 1960/4885MEN1 1806/4885KMT2A 388/4885
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides ATL3, PDIA3, NAT1 ALDH1A1 163/4885MEN1 4000/4885KMT2A 2789/4885
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides CYP4B1, ARSA, C1S ALDH1A1 589/4885MEN1 3204/4885KMT2A 2851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.