Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407617 | 0.89 | ENPP2 (0.62) | ENPP2BCHELTA4HEPHX2MEN1 | |
| SCHEMBL17609087 | 0.84 | LTA4H (0.63) | BCHELTB4RLTB4R2LTA4HEPHX2 | |
| SCHEMBL11473762 | 0.80 | LTA4H (0.66) | BCHELTA4HEPHX2MEN1KMT2A | |
| SCHEMBL17602199 | 0.80 | BCHE (0.49) | BCHEALOX5NOX1 | |
| SCHEMBL17609267 | 0.79 | MAOB (0.54) | LTA4HALOX5APPNOX1 | |
| SCHEMBL17609128 | 0.78 | ALOX5 (0.54) | BCHELTB4RLTB4R2ALOX5APP | |
| SCHEMBL25262863 | 0.78 | APP (0.64) | ENPP2BCHEMEN1KMT2AFFAR1 | |
| SCHEMBL17609148 | 0.78 | MEN1 (0.68) | ENPP2BCHEMEN1KMT2A | |
| SCHEMBL10406182 | 0.78 | TDP1 (0.64) | BCHELTA4HEPHX2MEN1KMT2A | |
| SCHEMBL17609119 | 0.77 | ESR1 (0.45) | ENPP2LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193601-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044429-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |