SCHEMBL176118

SCHEMBL176118

C=CCC(=O)OC(=O)C(N)(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11849329 0.83
SCHEMBL5242143 0.83 TSHR (0.36) TSHR
SCHEMBL9065953 0.81
SCHEMBL137424 0.76 ALDH1A1 (0.41) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL462526 0.73 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL777025 0.73
SCHEMBL252925 0.72 HTT (0.35) ALDH1A1KMT2ATSHR
SCHEMBL20603229 0.71 MEN1 (0.39) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL775184 0.70
SCHEMBL25439707 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1816 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240122877-A1 ORAL AMPHETAMINE COMPOSITION ADARE PHARMACEUTICALS, INC. 2024-04-18 US claimed
US-11896562-B2 Oral amphetamine composition ADARE PHARMACEUTICALS, INC. (US) 2024-02-13 US claimed
EP-3613404-B1 METHOD FOR PRODUCING FILM KAO CORP (JP) 2023-09-13 EP claimed
WO-2023152773-A1 SOLID FORMS OF MOMELOTINIB SALTS AND IMPROVED PROCESSES FOR THE PREPARATION OF MOMELOTINIB DR. REDDY'S INSTITUTE OF LIFE SCIENCES (IN) 2023-08-17 WO claimed
US-20230240994-A1 MEDICAMENT-CONTAINING HOLLOW PARTICLE Sumitomo Pharma Co., Ltd. (JP) 2023-08-03 US claimed
US-11623920-B2 Process for preparing pitolisant hydrochloride and solid-state forms thereof NURAY CHEMICALS PRIVATE LIMITED (IN) 2023-04-11 US claimed
US-20220402886-A1 PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF Nuray Chemicals Private Lmiited (IN) 2022-12-22 US claimed
CN-113056262-B Prolyl hydroxylase inhibitor pharmaceutical composition and preparation method thereof 江苏恒瑞医药股份有限公司 2022-11-18 CN claimed
CN-112641718-B Taste-masking compound based on porous carrier and preparation method and application thereof 山东大学 2022-07-29 CN claimed
US-20220160693-A1 PHARMACEUTICAL COMPOSITION OF PROLYL HYDROXYLASE INHIBITOR AND PREPARATION METHOD THEREFOR JIANGSU HENGRUI MEDICINE CO., LTD. (CN) 2022-05-26 US claimed
US-5382567-A Perfumes including cyclodextrin coatings and a pH solution and gastric coating WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-01-17 US claimed
EP-0570606-A1 Orally administrable solid medicine and process for preparing the same Wakamoto Pharmaceutical Co., Ltd. (JP) 1993-11-24 EP claimed
US-5258375-A Polyvinyl acetal diethylaminoacetate as a stabilizer SS PHARMACEUTICAL CO., LTD. (JP) 1993-11-02 US claimed
US-5244669-A Multilayer coating MITSUBISHI KASEI CORPORATION (JP) 1993-09-14 US claimed
EP-0387808-B1 COMPOSITIONS FOR THE PREPARATION OF DOSAGE-FORM ACTIVE VITAMINS D3 AND PROCESS FOR PREPARING STABLE DOSAGE-FORM ACTIVE VITAMINS D3 BY USING THE SAME SS PHARMACEUTICAL CO., LTD. (JP) 1993-05-12 EP claimed
EP-0387808-A2 Compositions for the preparation of dosage-form active vitamins D3 and process for preparing stable dosage-form active vitamins D3 by using the same SS PHARMACEUTICAL CO., LTD. (JP) 1990-09-19 EP claimed
US-4609640-A WATER-SOLUBLE MACROMOLECULE CHELATING AGENTS TOYO JOZO COMPANY, LTD. (JP) 1986-09-02 US claimed
US-4443497-A DISSOLVING, COATING, SOLVENTS, POLYMER, ETHYL CELLULOSE, ANTICOAGULANTS, DRUGS TANABE SEIYAKU CO., LTD. (JP) 1984-04-17 US claimed
US-4404183-A PARTICLE MIXTURE OF POLYOXYETHYLENE GLYCOL AND INDOMETHACIN OR NICARDIPINE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-09-13 US claimed
US-4343789-A NICARDIPINE AND POLYOXYETHYLENE GLYCOL YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1982-08-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160693-A1 PHARMACEUTICAL COMPOSITION OF PROLYL HYDROXYLASE INHIBITOR AND PREPARATION METHOD THEREFOR P4HA1, EGLN2, EGLN3 ALDH1A1 429/4885MEN1 2950/4885CYP1A2 290/4885
US-20220402886-A1 PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF PITHD1, MLN, TPP1 ALDH1A1 810/4885MEN1 1690/4885CYP1A2 322/4885
US-11623920-B2 Process for preparing pitolisant hydrochloride and solid-state forms thereof PITHD1, MLN, TPP1 ALDH1A1 810/4885MEN1 1690/4885CYP1A2 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.