Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.45 |
| ▸ | LCK | P06239 | 5/20 | 0.45 |
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | BMX | P51813 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | YES1 | P07947 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | FGR | P09769 | 1/20 | 0.45 |
| ▸ | CSK | P41240 | 1/20 | 0.45 |
| ▸ | BLK | P51451 | 1/20 | 0.45 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612997 | 0.84 | DDR2 (0.50) | ABL1BCRKITRETNTRK3 | |
| SCHEMBL12398650 | 0.84 | ABL1 (0.42) | ABL1LCKCSF1RSRCBMX | |
| SCHEMBL12398649 | 0.84 | GPR142 (0.56) | ABL1BCRGPR142 | |
| SCHEMBL17612913 | 0.78 | ABL1 (0.48) | ABL1BCRKIT | |
| SCHEMBL17612910 | 0.77 | BRAF (0.40) | — | |
| SCHEMBL17612957 | 0.77 | ABL1 (0.38) | ABL1CSF1RHCKBCRKDR | |
| SCHEMBL17612975 | 0.76 | DDR2 (0.45) | ABL1BCRKITRETDDR2 | |
| SCHEMBL17612954 | 0.76 | ALDH1A1 (0.40) | MAPK14 | |
| SCHEMBL17612912 | 0.76 | ABL1 (0.51) | ABL1BCRKIT | |
| SCHEMBL17612934 | 0.75 | MCHR1 (0.43) | ABL1GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |