Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613248 | 0.76 | RIPK1 (0.39) | — | |
| SCHEMBL8388694 | 0.66 | — | — | |
| SCHEMBL4607927 | 0.65 | MAPT (0.36) | LMNAL3MBTL1 | |
| SCHEMBL18901147 | 0.61 | — | — | |
| SCHEMBL11919177 | 0.59 | KMT2A (0.39) | LMNA | |
| SCHEMBL762438 | 0.58 | — | — | |
| SCHEMBL2208379 | 0.58 | HPGD (0.39) | LMNAL3MBTL1 | |
| SCHEMBL1785878 | 0.58 | POLB (0.36) | — | |
| SCHEMBL12049735 | 0.57 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL13285783 | 0.56 | RIPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788333-B1 | 1,2,4-TRIAZOLES AS ALLOSTERIC MODULATORS OF MGLU5 RECEPTOR ACTIVITY FOR THE TREATMENT OF SCHIZOPHRENIA OF DEMENTIA | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |