Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613745 | 0.92 | RAB9A (0.36) | RAB9ATSHRKDM4ESMN1; SMN2HRH4 | |
| SCHEMBL17613756 | 0.83 | KDM4E (0.32) | TSHRKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL17613606 | 0.79 | TSHR (0.37) | TSHRKDM4ESMN1; SMN2ALDH1A1PAOX | |
| SCHEMBL17613723 | 0.78 | TSHR (0.32) | TSHRMAPK1MEN1KMT2AMAPT | |
| SCHEMBL12022467 | 0.76 | — | — | |
| SCHEMBL17613686 | 0.76 | DNM1 (0.34) | TSHRKDM4ESMN1; SMN2ALDH1A1PAOX | |
| SCHEMBL17613666 | 0.75 | TSHR (0.39) | TSHRKDM4ESMN1; SMN2MAPK1MEN1 | |
| SCHEMBL12023038 | 0.74 | TSHR (0.46) | TSHRKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7777520 | 0.73 | TSHR (0.54) | TSHRKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL23015988 | 0.72 | MEN1 (0.46) | RAB9ATSHRKDM4ECCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |