Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 6/20 | 0.33 |
| ▸ | THRA | P10827 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613741 | 0.92 | RAB9A (0.35) | RAB9ATSHRMAPK1MEN1KMT2A | |
| SCHEMBL17613686 | 0.84 | DNM1 (0.34) | TSHRMAPK1MEN1KMT2ADNM1 | |
| SCHEMBL17613606 | 0.83 | TSHR (0.37) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL17613723 | 0.82 | TSHR (0.32) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL17613594 | 0.79 | HRH4 (0.34) | RAB9ADNM1THRBTHRACHRM2 | |
| SCHEMBL17613756 | 0.78 | KDM4E (0.32) | TSHRMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL17613666 | 0.77 | TSHR (0.39) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL17613689 | 0.76 | KDM4E (0.35) | DNM1THRBTHRAMAPTCHRM2 | |
| SCHEMBL12023038 | 0.76 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL12022634 | 0.75 | RAB9A (0.30) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |