Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CASP1 | P29466 | 1/20 | 0.69 |
| ▸ | CASP7 | P55210 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498577 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL4280023 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL27816591 | 0.87 | RAB9A (0.69) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL7870469 | 0.86 | ALDH1A1 (0.89) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL14854089 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL5999214 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL593023 | 0.83 | MEN1 (0.65) | ALDH1A1KDM4EGAARAB9AHPGD | |
| SCHEMBL16139778 | 0.83 | KDM4E (0.62) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL4319368 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL5999215 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099560-A1 | ELECTROCHEMICAL SENSOR SYSTEM COMPRISING MOLECULARLY IMPRINTED POLYMER FOR EARLY WARNING OF URINARY TRACT INFECTIONS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2020-05-22 | — | — | WO | claimed |
| CN-106396438-B | A kind of environment protecting cement | 邯郸金隅太行水泥有限责任公司 | 2018-08-28 | — | — | CN | claimed |
| CN-106396438-A | Environment-friendly cement | 许勤峰 | 2017-02-15 | — | — | CN | claimed |
| CN-106237994-A | A kind of hexavalent chromium adsorbent and application thereof | 许勤峰 | 2016-12-21 | — | — | CN | claimed |
| US-8586746-B2 | Amino-aza-adamantane derivatives and methods of use | ABBVIE INC. (US) | 2013-11-19 | — | — | US | claimed |
| EP-2069289-B1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS | SANOFI SA (FR) | 2013-10-02 | — | — | EP | claimed |
| CN-101516834-B | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI AVENTIS | 2013-04-03 | — | — | CN | claimed |
| EP-2476681-A2 | Amino-aza-adamantane derivatives and methods of use | Abbott Laboratories (US) | 2012-07-18 | — | — | EP | claimed |
| US-20090233949-A1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | claimed |
| EP-1971599-A1 | ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1926731-A2 | AMINO-AZA-ADAMANTANE DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-06-04 | — | — | EP | claimed |
| WO-2007071434-A1 | ANTIVIRAL 2-CARBOXY-THIOPHENE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-28 | — | — | WO | claimed |
| WO-2007038058-A2 | AMINO-AZA-ADAMANTANE DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-04-05 | — | — | WO | claimed |
| US-20070072892-A1 | Amino-aza-adamantane derivatives and methods of use | ABBOTT LABORATORIES | 2007-03-29 | — | — | US | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | UNIVERSITEIT ANTWERPEN (BE) | 2024-07-11 | — | — | US | disclosed |
| US-20240110914-A1 | Devices and Methods for Detection of Viruses from Exhaled Breath | NATIONAL SCIENCE FOUNDATION | 2024-04-04 | — | — | US | disclosed |
| US-5747525-A | ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1998-05-05 | — | — | US | disclosed |
| US-5602170-A | ADMINISTERING ANTIIFLAMMATORY AGENT | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1997-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072892-A1 | Amino-aza-adamantane derivatives and methods of use | CHRNA7, CHRNA5, CHRNA1 | ALDH1A1 1034/4885KDM4E 1441/4885LMNA 2815/4885 |
| US-20090233949-A1 | ISOSERINE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, F2, F9 | ALDH1A1 3166/4885KDM4E 3870/4885LMNA 2062/4885 |
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | ILK, MTCL3, FTO | ALDH1A1 979/4885KDM4E 146/4885LMNA 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.