Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680750 | 0.82 | LMNA (0.56) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL902112 | 0.80 | LMNA (0.57) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL22796564 | 0.78 | TP53 (0.85) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL22796708 | 0.77 | LMNA (0.65) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL22796563 | 0.77 | LMNA (0.70) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL22680749 | 0.75 | LMNA (0.70) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL902657 | 0.74 | TP53 (0.60) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL902831 | 0.74 | ALDH1A1 (0.83) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL17616166 | 0.73 | HSD17B10 (0.53) | LMNATP53ALDH1A1HPGDKDM4E | |
| SCHEMBL902473 | 0.72 | HSD17B10 (0.57) | LMNATP53ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200360381-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTION AND OTHER VIRAL INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200360381-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTION AND OTHER VIRAL INFECTIONS | F3, CD4, F12 | LMNA 2345/4885TP53 1325/4885ALDH1A1 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.