Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17615168 | 0.84 | AGXT (0.42) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL18583796 | 0.82 | RCE1 (0.43) | ALDH1A1TSHRIDO1AGXTMAOB | |
| SCHEMBL14567491 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL3952054 | 0.77 | IDO1 (0.48) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL6550926 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL6884424 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL8964616 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL13392810 | 0.76 | CA1 (0.51) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL17900959 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL28733925 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | ALDH1A1, ALDH3A1, ADH1A | ALDH1A1 1/4885TP53 3696/4885CYP3A4 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.