SCHEMBL17617871

SCHEMBL17617871

COP(=O)(CCCCCCc1ccc2ccc3ccc(CCCCCCP(=O)(O)O)nc3c2n1)OC

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 11/20 0.35
S1PR1 P21453 9/20 0.35
S1PR2 O95136 8/20 0.35
S1PR4 O95977 5/20 0.35
LPAR2 Q9HBW0 4/20 0.34
LPAR3 Q9UBY5 3/20 0.34
CCR1 P32246 2/20 0.34
PDE10A Q9Y233 1/20 0.34
S1PR5 Q9H228 1/20 0.33
KCNH2 Q12809 1/20 0.31
ENPP2 Q13822 1/20 0.31
CETP P11597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17617876 0.93 CCR1 (0.39) CCR1PDE10AKCNH2
SCHEMBL18380194 0.91 S1PR1 (0.34) S1PR3S1PR1S1PR2S1PR4CCR1
SCHEMBL17617875 0.86 CCR1 (0.38) CCR1PDE10A
SCHEMBL17617873 0.81 PDE10A (0.41) CCR1PDE10A
SCHEMBL17617874 0.74 PGK1 (0.49) CCR1PDE10A
SCHEMBL17617872 0.71 CCR1 (0.42) CCR1PDE10A
SCHEMBL31026592 0.67 KCNH2 (0.64) CCR1KCNH2
SCHEMBL10531797 0.67 KCNH2 (0.64) CCR1KCNH2
SCHEMBL11515947 0.66 FAAH (0.46) LPAR2LPAR3
SCHEMBL8949633 0.65 SIGMAR1 (0.50) S1PR3S1PR1S1PR2S1PR4CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548373-B2 Nonvolatile semiconductor memory device KABUSHIKI KAISHA TOSHIBA (JP) 2017-01-17 US disclosed
US-20160087067-A1 NONVOLATILE SEMICONDUCTOR MEMORY DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-24 US disclosed