SCHEMBL17618194

SCHEMBL17618194

COC(=O)c1cc2sccc2cc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.50
ALDH1A1 P00352 7/20 0.49
GAA P10253 6/20 0.49
HSD17B10 Q99714 4/20 0.49
MAPT P10636 4/20 0.49
HPGD P15428 3/20 0.49
GLA P06280 2/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
ABL1 P00519 1/20 0.47
TSHR P16473 2/20 0.46
ALOX15 P16050 1/20 0.46
CFTR P13569 4/20 0.45
NPC1 O15118 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19664232 0.87 SMN1; SMN2 (0.44) KDM4EALDH1A1HSD17B10MAPTHPGD
SCHEMBL3814050 0.79 ALDH1A1 (0.49) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL6976362 0.79 RAB9A (0.44) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL3816198 0.78 MAPT (0.42) KDM4EALDH1A1HSD17B10MAPTHPGD
SCHEMBL3818091 0.78 KMT2A (0.42) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL15133575 0.76 KDM4E (0.63) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL20748823 0.76 GAA (0.33) KDM4EALDH1A1GAATSHRNPC1
SCHEMBL4758833 0.75 KDM4E (0.73) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL30393412 0.75 ALDH1A1 (0.61) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL266131 0.75 ALDH1A1 (0.61) KDM4EALDH1A1GAAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125346-A1 Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4709711-A1 ISOQUINOLINONE DERIVATIVES AND 4H-QUINOLIZINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE Beone Medicines I GmbH (CH) 2026-03-18 EP disclosed
WO-2024230803-A1 ISOQUINOLINONE DERIVATIVES AND 4H-QUINOLIZINONE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE BEIGENE, LTD. (GB) 2024-11-14 WO disclosed
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP disclosed
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP disclosed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US disclosed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US disclosed
EP-3444257-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Boe Technology Group Co. Ltd. (CN) 2019-02-20 EP disclosed
EP-3444257-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Boe Technology Group Co. Ltd. (CN) 2019-02-20 EP disclosed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US disclosed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US disclosed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US disclosed
US-9515268-B2 Aromatic amine derivatives and preparation method, uses and organic electroluminescent devices thereof BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-12-06 US disclosed
US-9515268-B2 Aromatic amine derivatives and preparation method, uses and organic electroluminescent devices thereof BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-12-06 US disclosed
US-20160087221-A1 AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-03-24 US disclosed
US-20160087221-A1 AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES SLC26A3, SLCO2A1, SLCO2B1 KDM4E 3315/4885ALDH1A1 602/4885GAA 4165/4885
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices SLC26A3, SLCO2A1, SLCO2B1 KDM4E 3315/4885ALDH1A1 602/4885GAA 4165/4885
US-20160087221-A1 AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF C1S, C5, C9 KDM4E 409/4885ALDH1A1 709/4885GAA 4588/4885
US-20260125346-A1 Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease NR3C1, NR3C2, PIK3R4 KDM4E 3237/4885ALDH1A1 1598/4885GAA 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.