Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761470 | 0.92 | DHODH (0.40) | DGAT1CSGALNACT1DHODHCFTR | |
| SCHEMBL1761324 | 0.91 | MAPK14 (0.36) | DGAT1CSGALNACT1HPGDSTAS1R3TAS1R1 | |
| SCHEMBL1761762 | 0.89 | DGAT1 (0.47) | DGAT1CSGALNACT1DHODHHPGDSCNR2 | |
| Trifluoroacetic Acid SCHEMBL1761830 | 0.88 | DGAT1 (0.46) | DGAT1CSGALNACT1DHODHHPGDSCNR2 | |
| SCHEMBL1761530 | 0.88 | PDE4B (0.39) | DGAT1CSGALNACT1DHODHCNR2CFTR | |
| SCHEMBL1761354 | 0.88 | DGAT1 (0.44) | DGAT1CSGALNACT1DHODHTAS1R3TAS1R1 | |
| SCHEMBL1761407 | 0.87 | DGAT1 (0.42) | DGAT1CSGALNACT1DHODHCNR2CFTR | |
| SCHEMBL1761327 | 0.83 | DGAT1 (0.36) | DGAT1CSGALNACT1DHODH | |
| SCHEMBL1762132 | 0.82 | DGAT1 (0.47) | DGAT1CSGALNACT1DHODHCFTR | |
| Trifluoroacetic Acid SCHEMBL1761467 | 0.82 | DGAT1 (0.45) | DGAT1CSGALNACT1DHODHCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118302-A1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7759376-B2 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, PGC | DGAT1 486/4885CSGALNACT1 3157/4885DHODH 2149/4885 |
| US-20110118302-A1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | FABP4, GPR119, PGC | DGAT1 486/4885CSGALNACT1 3157/4885DHODH 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.