Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963995 | 0.90 | PRMT5 (0.39) | KDM5AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30552413 | 0.78 | GPR119 (0.42) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL31187123 | 0.78 | GPR119 (0.42) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL29072059 | 0.75 | PARP1 (0.47) | — | |
| SCHEMBL30781994 | 0.73 | KDM5A (0.37) | KDM5AP2RX7RIPK1CYP11B2 | |
| SCHEMBL15529641 | 0.73 | CHRNA7 (0.51) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL17620844 | 0.72 | KDM5A (0.48) | KDM5AP2RX7CYP1A2SLC6A7 | |
| SCHEMBL38659451 | 0.72 | HSD11B1 (0.51) | RIPK1ALDH1A1DPP4 | |
| SCHEMBL8296762 | 0.72 | HSD11B1 (0.51) | RIPK1ALDH1A1DPP4 | |
| SCHEMBL31590042 | 0.71 | ALDH1A1 (0.44) | ALDH1A1NPSR1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296723-B2 | NAMPT inhibitors | ABBVIE INC. (US) | 2016-03-29 | — | — | US | disclosed |