SCHEMBL17622174

SCHEMBL17622174

CC1(C)c2ccccc2N(c2cccc3c2C(=O)N(C2CCCCC2N2C(=O)c4cccc(N5c6ccccc6C(C)(C)c6ccccc65)c4C2=O)C3=O)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 8/20 0.42
CRBN Q96SW2 8/20 0.42
PGR P06401 8/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TNF P01375 1/20 0.38
IL1B P01584 1/20 0.38
TBXA2R P21731 1/20 0.38
IKZF1 Q13422 1/20 0.38
IKZF3 Q9UKT9 1/20 0.38
HTR2B P41595 2/20 0.37
TMEM97 Q5BJF2 2/20 0.37
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35
HTR3D Q70Z44 1/20 0.35
HTR3C Q8WXA8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17622170 0.80 PGR (0.50) PGRMEN1KMT2A
SCHEMBL13231542 0.74 KMT2A (0.44) MEN1KMT2A
SCHEMBL17622268 0.74 PGR (0.49) PGRMEN1KMT2A
SCHEMBL17643882 0.74 DPP4 (0.57) PGRMEN1KMT2A
SCHEMBL17622260 0.73 TMEM97 (0.40) DDB1CRBNTNFIL1BTBXA2R
SCHEMBL17622271 0.72 DPP4 (0.47) PGRMEN1KMT2A
SCHEMBL17974877 0.71 PGR (0.36) PGRMEN1KMT2A
SCHEMBL20019729 0.71 RAB9A (0.39) PGRMEN1KMT2A
SCHEMBL25495724 0.68 PGR (0.38) PGRMEN1KMT2A
SCHEMBL17643948 0.68 RAB9A (0.52) PGRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651394-B2 Organic molecules for use as emitters CYNORA GMBH (DE) 2020-05-12 US disclosed
EP-3246373-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2019-01-30 EP disclosed
EP-3137574-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2018-04-04 EP disclosed
EP-3246373-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-11-22 EP disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 WO disclosed