Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | RORA | P35398 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | RORB | Q92753 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19421869 | 0.86 | NR1H3 (0.44) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL17622319 | 0.84 | ALDH1A1 (0.47) | NR1H2BCHECES1ALDH1A1CASP3 | |
| SCHEMBL19421872 | 0.84 | PGR (0.35) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL17622295 | 0.83 | CA9 (0.44) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL19842376 | 0.83 | NR1H2 (0.43) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL16231003 | 0.83 | KIF11 (0.46) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL19421873 | 0.83 | PGR (0.37) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL19421875 | 0.82 | RORA (0.38) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL17622209 | 0.81 | TP53 (0.42) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL17622302 | 0.80 | CA9 (0.41) | PGRRORARORCRORBDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246373-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | cynora GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | disclosed |
| WO-2016042070-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |