Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD2 | P13995 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624388 | 0.81 | MTHFD2 (0.48) | MTHFD2ALDH1A1KDM4EHSD17B10BCHE | |
| SCHEMBL19498216 | 0.77 | MTHFD2 (0.44) | MTHFD2ALDH1A1KDM4EHSD17B10BCHE | |
| SCHEMBL11049965 | 0.69 | SMN1; SMN2 (0.53) | MTHFD2ALDH1A1KDM4EHSD17B10BCHE | |
| SCHEMBL19504425 | 0.69 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL11449986 | 0.68 | GAA (0.54) | MTHFD2ALDH1A1KDM4EHSD17B10BCHE | |
| SCHEMBL10860457 | 0.68 | ALDH1A1 (0.54) | MTHFD2ALDH1A1KDM4EHSD17B10TDP1 | |
| SCHEMBL10856015 | 0.67 | ALDH1A1 (0.55) | MTHFD2ALDH1A1KDM4EHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL10858250 | 0.67 | ALDH1A1 (0.52) | MTHFD2ALDH1A1KDM4EHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL10856957 | 0.66 | ALDH1A1 (0.54) | MTHFD2ALDH1A1KDM4EHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL11086720 | 0.65 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHSD17B10BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044604-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |