Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668846 | 0.84 | P2RX7 (0.40) | CTSSSMN1; SMN2CD38MEN1KMT2A | |
| SCHEMBL17624705 | 0.80 | CD38 (0.38) | CTSSSMN1; SMN2HCRTR1HCRTR2CD38 | |
| SCHEMBL669098 | 0.80 | ABCB1 (0.46) | TAS1R3TAS1R1 | |
| SCHEMBL16036752 | 0.80 | ABCB1 (0.46) | TAS1R3TAS1R1 | |
| SCHEMBL2682576 | 0.73 | TAS1R3 (0.48) | TAS1R3TAS1R1 | |
| SCHEMBL19946452 | 0.73 | TAS1R3 (0.48) | TAS1R3TAS1R1 | |
| SCHEMBL668773 | 0.71 | TAS1R3 (0.44) | PRSS1CTSGCTRB1CMA1TAS1R3 | |
| SCHEMBL22380835 | 0.71 | TAS1R3 (0.44) | PRSS1CTSGCTRB1CMA1TAS1R3 | |
| SCHEMBL28642784 | 0.71 | GABRA1 (0.39) | HCRTR1HCRTR2HTTCYP1A2CYP3A4 | |
| SCHEMBL19946411 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AHTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044390-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORPORATION (US) | 2016-03-24 | — | — | WO | disclosed |