Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625618 | 0.92 | KMT2A (0.41) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL17625220 | 0.91 | SIGMAR1 (0.49) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16202783 | 0.87 | LMNA (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14337468 | 0.86 | SIGMAR1 (0.64) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16202782 | 0.83 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17625617 | 0.76 | MAPT (0.35) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16202569 | 0.75 | ALDH1A1 (0.37) | SIGMAR1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL17625616 | 0.73 | SIGMAR1 (0.35) | SIGMAR1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL16202971 | 0.69 | KMT2A (0.65) | KMT2AMEN1ALOX15TSHRMAPT | |
| SCHEMBL17885425 | 0.69 | MAPT (0.69) | KMT2AMAPTALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-03-24 | — | — | US | disclosed |
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | HRH4, NR1H3, NR1H2 | SIGMAR1 128/4885GRIN2D 958/4885GRIN3B 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.