Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 10/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 10/20 | 0.36 |
| ▸ | GBA1 | P04062 | 9/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 3/20 | 0.31 |
| ▸ | LCT | P09848 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625660 | 0.95 | PTPN2 (0.36) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL17625645 | 0.91 | TDP1 (0.38) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL19407500 | 0.90 | GBA1 (0.32) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL17625628 | 0.90 | PTPN2 (0.41) | PTPN2PTPN1PTPN6TACR1ALDH1A1 | |
| SCHEMBL17625640 | 0.88 | TSHR (0.37) | PTPN2PTPN1PTPN6TACR1ALDH1A1 | |
| SCHEMBL17625648 | 0.87 | PTPN2 (0.36) | L3MBTL1TDP1PTPN2PTPN1PTPN6 | |
| SCHEMBL19407496 | 0.81 | ABCB1 (0.35) | PTPN2PTPN1PTPN6 | |
| SCHEMBL17625646 | 0.78 | CA1 (0.31) | — | |
| SCHEMBL17642475 | 0.77 | TDP1 (0.37) | L3MBTL1TDP1UGCGGBA2GBA1 | |
| SCHEMBL17625653 | 0.77 | ALDH1A1 (0.35) | PTPN2PTPN1PTPN6TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190157558-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-10256409-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-9938241-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | RDX, AOX1, ALDH1A2 | L3MBTL1 4165/4885TDP1 1943/4885UGCG 3834/4885 |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | L3MBTL1 3341/4885TDP1 3061/4885UGCG 4526/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | L3MBTL1 3341/4885TDP1 3061/4885UGCG 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.