Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625628 | 0.91 | PTPN2 (0.41) | TACR1ALDH1A1IDO1PTPN2PTPN1 | |
| SCHEMBL17625660 | 0.90 | PTPN2 (0.36) | TACR1ALDH1A1IDO1PTPN2PTPN1 | |
| SCHEMBL17625657 | 0.88 | L3MBTL1 (0.37) | TACR1ALDH1A1PTPN2PTPN1PTPN6 | |
| SCHEMBL17625648 | 0.88 | PTPN2 (0.36) | TACR1ALDH1A1PTPN2PTPN1PTPN6 | |
| SCHEMBL17625645 | 0.85 | TDP1 (0.38) | TACR1PTPN2PTPN1PTPN6 | |
| SCHEMBL17625653 | 0.84 | ALDH1A1 (0.35) | TACR1ALDH1A1PTPN2PTPN1PTPN6 | |
| SCHEMBL17625661 | 0.84 | PTPRZ1 (0.49) | PTPN2PTPN1PTPN6PTPRZ1 | |
| SCHEMBL19407496 | 0.82 | ABCB1 (0.35) | PTPN2PTPN1PTPN6 | |
| SCHEMBL17625646 | 0.81 | CA1 (0.31) | — | |
| SCHEMBL17625668 | 0.80 | PTPRZ1 (0.45) | PTPN2PTPN1PTPN6PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135831-A1 | POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES | PROMERUS, LLC (US) | 2022-05-05 | — | — | US | disclosed |
| US-20220135832-A1 | SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS | PROMERUS, LLC (US) | 2022-05-05 | — | — | US | disclosed |
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190157558-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-10256409-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-9938241-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | RDX, AOX1, ALDH1A2 | TSHR 2733/4885TACR1 2468/4885ALDH1A1 24/4885 |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | TSHR 2515/4885TACR1 2436/4885ALDH1A1 145/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | TSHR 2515/4885TACR1 2436/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.