SCHEMBL17626013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17625971	0.79	MAPT (0.42)	ALDH1A1MAPTSMN1; SMN2LMNANPC1
	SCHEMBL17625996	0.78	AR (0.40)	ARAPPALDH1A1MAPTSMN1; SMN2
	SCHEMBL2301856	0.76	ALDH1A1 (0.50)	ARALDH1A1MAPTKDM4EHPGD
	SCHEMBL17626170	0.75	HTT (0.42)	ALDH1A1MAPTSMN1; SMN2LMNAKDM4E
	SCHEMBL19626659	0.74	AR (0.47)	ARAPPALDH1A1MAPTKDM4E
	SCHEMBL17628653	0.74	HTT (0.38)	ARAPPALDH1A1MAPTSMN1; SMN2
	SCHEMBL19625488	0.74	AR (0.44)	ARAPPALDH1A1MAPTHSD17B10
	SCHEMBL17626235	0.73	MAPT (0.33)	ARALDH1A1MAPTNPC1RAB9A
	SCHEMBL4712823	0.72	CHKA (0.41)	ARALDH1A1MAPTSMN1; SMN2KDM4E
	SCHEMBL17625986	0.72	ALDH1A1 (0.38)	ALDH1A1MAPTSMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.