Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277090 | 0.83 | TDP2 (0.41) | CAMK2DALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL14854128 | 0.81 | TDP2 (0.43) | CAMK2DALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL15715363 | 0.78 | TDP2 (0.38) | CAMK2DALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL12424813 | 0.72 | TDP2 (0.43) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL2270426 | 0.71 | TDP2 (0.39) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL1799678 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL12424807 | 0.70 | ADORA2B (0.36) | CAMK2DALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL18170632 | 0.70 | TDP2 (0.41) | CAMK2DKDM4EPOLBMEN1KMT2A | |
| SCHEMBL12178007 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL1801873 | 0.67 | NAT1 (0.38) | ALDH1A1KDM4EHPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124703-A1 | MOLECULES COMPRISING A BIS(HETEROARYL)MALEIMIDE BACKBONE, AND USE THEREOF IN THE INHIBITION OF DDE/DDD ENZYMES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-26 | — | — | US | disclosed |
| EP-2240471-A1 | MOLECULES COMPRISING A BIS(HETEROARYL)MALEIMIDE BACKBONE, AND USE THEREOF IN THE INHIBITION OF DDE/DDD ENZYMES | Centre National de la Recherche Scientifique (FR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009098206-A1 | MOLECULES COMPRISING A BIS(HETEROARYL)MALEIMIDE BACKBONE, AND USE THEREOF IN THE INHIBITION OF DDE/DDD ENZYMES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124703-A1 | MOLECULES COMPRISING A BIS(HETEROARYL)MALEIMIDE BACKBONE, AND USE THEREOF IN THE INHIBITION OF DDE/DDD ENZYMES | DDT, DDC, DTD1 | CAMK2D 2502/4885ALDH1A1 1691/4885KDM4E 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.