Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | RAPGEF3 | O95398 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632381 | 0.79 | USP30 (0.48) | NPC1SMN1; SMN2 | |
| SCHEMBL17631915 | 0.77 | CDK9 (0.35) | FLT3 | |
| SCHEMBL17632787 | 0.73 | MEN1 (0.40) | — | |
| SCHEMBL17632085 | 0.73 | CDK9 (0.36) | FLT3CNR2 | |
| SCHEMBL17632600 | 0.72 | CDK9 (0.39) | SMN1; SMN2 | |
| SCHEMBL11391631 | 0.71 | NPC1 (0.41) | FLT3NPC1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL17631951 | 0.71 | SLC6A2 (0.38) | — | |
| SCHEMBL17632002 | 0.70 | CDK9 (0.41) | NPC1SMN1; SMN2 | |
| SCHEMBL17631866 | 0.70 | CDK9 (0.41) | NPC1SMN1; SMN2 | |
| SCHEMBL17632116 | 0.70 | CDK9 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |