Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631880 | 0.86 | SLC6A2 (0.35) | CDK9SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL17632098 | 0.85 | WNT1 (0.34) | SLC6A4SLC6A2SLC6A3CHEK2ABL1 | |
| SCHEMBL17631956 | 0.82 | USP30 (0.44) | USP30 | |
| SCHEMBL17632600 | 0.82 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632326 | 0.82 | USP30 (0.49) | CDK9CHEK1USP30 | |
| SCHEMBL17631943 | 0.82 | USP30 (0.49) | CDK9CHEK1USP30 | |
| SCHEMBL17632154 | 0.81 | RAB9A (0.38) | CDK9CHEK1 | |
| SCHEMBL17632245 | 0.81 | RAB9A (0.38) | CDK9CHEK1 | |
| SCHEMBL17631951 | 0.80 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3CHEK1KCNH2 | |
| SCHEMBL17632787 | 0.80 | MEN1 (0.40) | CDK9KCNH2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |