Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631866 | 0.82 | CDK9 (0.41) | CDK9REN | |
| SCHEMBL17632600 | 0.80 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632095 | 0.80 | USP30 (0.41) | CDK9 | |
| SCHEMBL17631671 | 0.80 | USP30 (0.41) | CDK9 | |
| SCHEMBL17632283 | 0.79 | MKNK1 (0.38) | CDK9TBK1 | |
| SCHEMBL17631644 | 0.79 | CDK9 (0.40) | CDK9TBK1 | |
| SCHEMBL17631709 | 0.77 | FLT3 (0.43) | FLT3 | |
| SCHEMBL17632787 | 0.76 | MEN1 (0.40) | CDK9RENMAPK1MEN1CYP2D6 | |
| SCHEMBL17632116 | 0.75 | CDK9 (0.38) | CDK9 | |
| SCHEMBL17632617 | 0.75 | CDK9 (0.42) | CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |