Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631951 | 0.82 | SLC6A2 (0.38) | — | |
| SCHEMBL17632787 | 0.82 | MEN1 (0.40) | KMT2ACDK9 | |
| SCHEMBL17631943 | 0.79 | USP30 (0.49) | CDK9 | |
| SCHEMBL17632002 | 0.79 | CDK9 (0.41) | SMN1; SMN2ABL1CDK9 | |
| SCHEMBL17632326 | 0.79 | USP30 (0.49) | CDK9 | |
| SCHEMBL17631859 | 0.78 | USP30 (0.39) | ABL1 | |
| SCHEMBL17632146 | 0.78 | USP30 (0.41) | KMT2ACDK9 | |
| SCHEMBL17632600 | 0.77 | CDK9 (0.39) | KDM4EHTTSMN1; SMN2CDK9 | |
| SCHEMBL17631958 | 0.77 | MKNK1 (0.45) | ABL1 | |
| SCHEMBL17632076 | 0.77 | USP30 (0.39) | ABL1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |