Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631943 | 0.90 | USP30 (0.49) | USP30CHEK1 | |
| SCHEMBL17632326 | 0.90 | USP30 (0.49) | USP30CHEK1 | |
| SCHEMBL17631958 | 0.89 | MKNK1 (0.45) | USP30ABL1CHEK1KDM1ADYRK1B | |
| SCHEMBL17632146 | 0.89 | USP30 (0.41) | USP30KDM1ATLR9TLR8TLR7 | |
| SCHEMBL17632076 | 0.85 | USP30 (0.39) | USP30ABL1 | |
| SCHEMBL17631696 | 0.83 | USP30 (0.41) | USP30ABL1KDM1ATLR9TLR8 | |
| SCHEMBL17632617 | 0.83 | CDK9 (0.42) | USP30CHEK1KDM1ADYRK1BMKNK1 | |
| SCHEMBL17632423 | 0.82 | CDK9 (0.40) | USP30ABL1 | |
| SCHEMBL17632787 | 0.82 | MEN1 (0.40) | USP30KDM1A | |
| SCHEMBL17631951 | 0.82 | SLC6A2 (0.38) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |