Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631943 | 1.00 | USP30 (0.49) | USP30CDK9FAAHF10GRIN2B | |
| SCHEMBL17631958 | 0.90 | MKNK1 (0.45) | USP30CHEK1 | |
| SCHEMBL17632146 | 0.90 | USP30 (0.41) | USP30CDK9GRIN2B | |
| SCHEMBL17631859 | 0.90 | USP30 (0.39) | USP30CHEK1 | |
| SCHEMBL17631696 | 0.89 | USP30 (0.41) | USP30CDK9GRIN2B | |
| SCHEMBL17632076 | 0.88 | USP30 (0.39) | USP30CDK9FAAH | |
| SCHEMBL17632423 | 0.87 | CDK9 (0.40) | USP30CDK9GRIN2B | |
| SCHEMBL17631671 | 0.84 | USP30 (0.41) | USP30CDK9FAAHF10 | |
| SCHEMBL17632095 | 0.84 | USP30 (0.41) | USP30CDK9FAAHF10 | |
| SCHEMBL17632335 | 0.83 | USP30 (0.41) | USP30CDK9FAAHF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |