Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631943 | 0.88 | USP30 (0.49) | USP30CDK9FAAH | |
| SCHEMBL17632326 | 0.88 | USP30 (0.49) | USP30CDK9FAAH | |
| SCHEMBL17632600 | 0.87 | CDK9 (0.39) | CDK9MAPKAPK2 | |
| SCHEMBL17631958 | 0.85 | MKNK1 (0.45) | USP30ABL1KCNH2GSK3BDYRK1A | |
| SCHEMBL17631859 | 0.85 | USP30 (0.39) | USP30ABL1 | |
| SCHEMBL17632423 | 0.84 | CDK9 (0.40) | USP30ABL1CDK9 | |
| SCHEMBL17632146 | 0.83 | USP30 (0.41) | USP30CDK9KCNH2 | |
| SCHEMBL17631696 | 0.82 | USP30 (0.41) | USP30ABL1CDK9KCNH2SYK | |
| SCHEMBL17631951 | 0.80 | SLC6A2 (0.38) | KCNH2 | |
| SCHEMBL17632787 | 0.80 | MEN1 (0.40) | USP30CDK9KCNH2SYKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |