Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632326 | 0.87 | USP30 (0.49) | CDK9USP30GRIN2B | |
| SCHEMBL17631943 | 0.87 | USP30 (0.49) | CDK9USP30GRIN2B | |
| SCHEMBL17632146 | 0.86 | USP30 (0.41) | CDK9USP30GRIN2BMEN1CYP2D6 | |
| SCHEMBL17631696 | 0.85 | USP30 (0.41) | CDK9USP30ABL1GRIN2B | |
| SCHEMBL17632076 | 0.84 | USP30 (0.39) | CDK9USP30ABL1 | |
| SCHEMBL17632787 | 0.84 | MEN1 (0.40) | CDK9USP30MEN1CYP2D6KMT2A | |
| SCHEMBL17631958 | 0.82 | MKNK1 (0.45) | USP30ABL1HDAC1HDAC2CYP1A2 | |
| SCHEMBL17631859 | 0.82 | USP30 (0.39) | USP30ABL1 | |
| SCHEMBL17631951 | 0.79 | SLC6A2 (0.38) | — | |
| SCHEMBL17632600 | 0.79 | CDK9 (0.39) | CDK9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |