Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 12/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632567 | 0.85 | BRD4 (0.47) | USP30UCHL1MAP4K1BRD4 | |
| SCHEMBL17632490 | 0.84 | MAPT (0.43) | MAPT | |
| SCHEMBL17632035 | 0.82 | ABL1 (0.45) | ABL1KITPDGFRAMAP4K1 | |
| SCHEMBL17632007 | 0.82 | LIPG (0.41) | ABL1MAP4K1 | |
| SCHEMBL17631942 | 0.81 | MAP4K1 (0.34) | ABL1KITPDGFRAMAP4K1MAPT | |
| SCHEMBL17631550 | 0.81 | ABL1 (0.41) | ABL1MAP4K1MAPT | |
| SCHEMBL17632611 | 0.79 | RAB9A (0.37) | MAPT | |
| SCHEMBL17632023 | 0.79 | USP30 (0.42) | USP30UCHL1BRD4 | |
| SCHEMBL17632020 | 0.78 | MAPT (0.46) | USP30MAPT | |
| SCHEMBL17631984 | 0.78 | DYRK1A (0.33) | MAP4K1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |