Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.45 |
| ▸ | KIT | P10721 | 4/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632007 | 0.87 | LIPG (0.41) | ABL1MAP4K1 | |
| SCHEMBL17632567 | 0.87 | BRD4 (0.47) | MAP4K1 | |
| SCHEMBL17632490 | 0.86 | MAPT (0.43) | — | |
| SCHEMBL17631550 | 0.84 | ABL1 (0.41) | ABL1MAP4K1LCK | |
| SCHEMBL17631727 | 0.83 | MAPT (0.44) | — | |
| SCHEMBL17632164 | 0.83 | IKBKB (0.33) | LCK | |
| SCHEMBL17631887 | 0.82 | USP30 (0.44) | ABL1KITPDGFRAMAP4K1 | |
| SCHEMBL17632621 | 0.82 | ALDH1A1 (0.47) | — | |
| SCHEMBL17632611 | 0.82 | RAB9A (0.37) | — | |
| SCHEMBL17632020 | 0.81 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |