Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631706 | 0.81 | GAA (0.36) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17631911 | 0.75 | UCHL1 (0.45) | POLBPIK3CD | |
| SCHEMBL17632276 | 0.70 | F10 (0.41) | KDM4EHPGD | |
| SCHEMBL17632490 | 0.69 | MAPT (0.43) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17632104 | 0.69 | SLC6A2 (0.33) | — | |
| SCHEMBL17631689 | 0.69 | SMN1; SMN2 (0.35) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17632318 | 0.69 | GRM5 (0.41) | — | |
| SCHEMBL17632164 | 0.68 | IKBKB (0.33) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17631727 | 0.68 | MAPT (0.44) | POLBKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL17632538 | 0.68 | ALDH1A1 (0.51) | POLBKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |