Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631911 | 0.82 | UCHL1 (0.45) | CDK9JAK2JAK3 | |
| SCHEMBL17631689 | 0.81 | SMN1; SMN2 (0.35) | CDK9 | |
| SCHEMBL17631706 | 0.81 | GAA (0.36) | — | |
| SCHEMBL17632005 | 0.79 | — | — | |
| SCHEMBL17632085 | 0.78 | CDK9 (0.36) | CDK9 | |
| SCHEMBL17632036 | 0.77 | USP30 (0.50) | — | |
| SCHEMBL17631923 | 0.76 | UCHL1 (0.50) | — | |
| SCHEMBL17632487 | 0.76 | USP30 (0.41) | — | |
| SCHEMBL17632491 | 0.76 | CHEK1 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL17631612 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |