⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631689 | 0.80 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17632085 | 0.78 | CDK9 (0.36) | — | |
| SCHEMBL17632036 | 0.76 | USP30 (0.50) | — | |
| SCHEMBL17632104 | 0.76 | SLC6A2 (0.33) | — | |
| SCHEMBL17631911 | 0.76 | UCHL1 (0.45) | — | |
| SCHEMBL17632487 | 0.75 | USP30 (0.41) | — | |
| SCHEMBL17632491 | 0.75 | CHEK1 (0.42) | — | |
| SCHEMBL17632047 | 0.75 | USP30 (0.41) | — | |
| SCHEMBL17631555 | 0.75 | USP30 (0.33) | — | |
| SCHEMBL17632525 | 0.74 | CHEK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |