SCHEMBL1762883

SCHEMBL1762883

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccccc1-c1cc(F)cc(F)c1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GRM5 P41594 2/20 0.37
CSNK1E P49674 10/20 0.36
CSNK1D P48730 6/20 0.36
DHODH Q02127 1/20 0.35
MGLL Q99685 1/20 0.34
CTSA P10619 2/20 0.34
PDE10A Q9Y233 1/20 0.32
RET P07949 1/20 0.32
SQOR Q9Y6N5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1763152 0.91 CSNK1E (0.43) POLBCSNK1ECSNK1D
SCHEMBL1763063 0.90 MGLL (0.38) POLBCSNK1ECSNK1DDHODHMGLL
SCHEMBL3325668 0.87 POLB (0.38) POLBCTSA
SCHEMBL1762881 0.84 CSNK1D (0.41) POLBCSNK1ECSNK1DDHODH
SCHEMBL3329484 0.84 CSNK1D (0.41) POLBGRM5CSNK1ECSNK1DDHODH
SCHEMBL1763226 0.84 CSNK1E (0.41) POLBCSNK1ECSNK1DDHODHMGLL
SCHEMBL1762911 0.84 POLB (0.36) POLBCSNK1ECSNK1DDHODHMGLL
SCHEMBL1762833 0.83 PTGER4 (0.39) POLBGRM5
SCHEMBL1762849 0.81 HSD17B10 (0.44) POLBCSNK1ECSNK1D
SCHEMBL28930106 0.81 GRM2 (0.39) POLBCSNK1ECSNK1DPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263327-B2 Enzymatic method for the production of microcapsules BASF SE (DE) 2012-09-11 US disclosed
US-20110124590-A1 Oil-in-Water Emulsion Comprising Solvent, Water, Surfactant and Pesticide BASF SE (DE) 2011-05-26 US disclosed
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules BASF SE 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules MGAM, ACHE, BCHE POLB 565/4885GRM5 2191/4885CSNK1E 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.