SCHEMBL1763152

SCHEMBL1763152

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccccc1-c1cccc(F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 18/20 0.43
CSNK1D P48730 15/20 0.43
PLK4 O00444 1/20 0.39
CHEK1 O14757 1/20 0.39
AURKA O14965 1/20 0.39
DAPK3 O43293 1/20 0.39
CHEK2 O96017 1/20 0.39
CDK1 P06493 1/20 0.39
PIM1 P11309 1/20 0.39
FGFR1 P11362 1/20 0.39
PRKACA P17612 1/20 0.39
FLT1 P17948 1/20 0.39
FGFR3 P22607 1/20 0.39
RPS6KB1 P23443 1/20 0.39
CDK2 P24941 1/20 0.39
MARK3 P27448 1/20 0.39
MAPK1 P28482 1/20 0.39
AKT1 P31749 1/20 0.39
FLT4 P35916 1/20 0.39
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1762883 0.91 POLB (0.38) CSNK1ECSNK1DPOLB
SCHEMBL1762833 0.88 PTGER4 (0.39) POLB
SCHEMBL1763063 0.85 MGLL (0.38) CSNK1ECSNK1DPOLB
SCHEMBL3329484 0.84 CSNK1D (0.41) CSNK1ECSNK1DPLK4AURKADAPK3
SCHEMBL1763226 0.84 CSNK1E (0.41) CSNK1ECSNK1DPOLB
SCHEMBL28483200 0.83 CSNK1E (0.41) CSNK1ECSNK1D
SCHEMBL3325668 0.83 POLB (0.38) FGFR1FGFR3KDRPOLB
SCHEMBL1762881 0.82 CSNK1D (0.41) CSNK1ECSNK1DAURKACDK2PLK1
SCHEMBL1762911 0.82 POLB (0.36) CSNK1ECSNK1DPOLB
SCHEMBL28248772 0.81 POLB (0.51) CSNK1ECSNK1DPIM1FGFR1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263327-B2 Enzymatic method for the production of microcapsules BASF SE (DE) 2012-09-11 US disclosed
US-20110124590-A1 Oil-in-Water Emulsion Comprising Solvent, Water, Surfactant and Pesticide BASF SE (DE) 2011-05-26 US disclosed
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules BASF SE 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules MGAM, ACHE, BCHE CSNK1E 1043/4885CSNK1D 1071/4885PLK4 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.