Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632072 | 0.82 | NPC1 (0.48) | NPC1RAB9APARP10ATMALDH1A1 | |
| SCHEMBL4248899 | 0.81 | SENP7 (0.37) | NPC1RAB9AKMT2ASENP7ALDH1A1 | |
| SCHEMBL17513876 | 0.79 | GRM5 (0.39) | NPC1RAB9APARP10SENP7PARP1 | |
| SCHEMBL17514018 | 0.74 | KMT2A (0.35) | NPC1RAB9AKDM4EATMKMT2A | |
| SCHEMBL17513938 | 0.73 | CA12 (0.39) | NPC1RAB9AATMFFAR1ALDH1A1 | |
| SCHEMBL4988520 | 0.69 | SIRT2 (0.43) | NPC1KDM4EPARP10KMT2AALDH1A1 | |
| SCHEMBL17513978 | 0.68 | ATM (0.41) | NPC1RAB9AATMSENP7ALDH1A1 | |
| SCHEMBL8885349 | 0.64 | KMT2A (0.53) | WEE1KDM4EATMKMT2AALDH1A1 | |
| SCHEMBL4986019 | 0.63 | CYP3A4 (0.43) | NPC1RAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL17514014 | 0.63 | ATM (0.53) | NPC1RAB9AATMKMT2ASENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |