Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513904 | 0.88 | GPR52 (0.43) | NPC1RAB9AATMPARP1PARP2 | |
| SCHEMBL17513978 | 0.86 | ATM (0.41) | NPC1RAB9AATMPARP1TSHR | |
| SCHEMBL17513997 | 0.80 | GRM5 (0.41) | NPC1RAB9APARP1GPR52ALDH1A1 | |
| SCHEMBL17514014 | 0.78 | ATM (0.53) | NPC1RAB9AATMTSHRFFAR1 | |
| SCHEMBL17514002 | 0.77 | RAB9A (0.40) | NPC1RAB9AATMTSHRL3MBTL1 | |
| SCHEMBL17513922 | 0.77 | NPC1 (0.38) | NPC1RAB9ATSHRFFAR1POLB | |
| SCHEMBL17513894 | 0.76 | ALOX5 (0.36) | CA12CA1CA2CA3CA4 | |
| SCHEMBL17513901 | 0.74 | GPR52 (0.40) | NPC1RAB9ATSHRPOLBL3MBTL1 | |
| SCHEMBL17513952 | 0.73 | NPC1 (0.46) | NPC1RAB9AATMTSHRFFAR1 | |
| SCHEMBL17632277 | 0.73 | NPC1 (0.34) | NPC1RAB9AATMPARP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182992-A1 | METHODS OF TREATING MILD BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2017075535-A1 | METHODS OF TREATING NEURODEGENERATIVE CONDITIONS | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2016028826-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |