Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513978 | 0.90 | ATM (0.41) | ATMMAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL17513966 | 0.89 | GRM5 (0.43) | ATMMAPTHPGDNPSR1HDAC1 | |
| SCHEMBL18797895 | 0.83 | LMNA (0.38) | ATMMAPTALDH1A1TSHRRAB9A | |
| SCHEMBL17513960 | 0.81 | L3MBTL1 (0.43) | ATMALDH1A1RAB9ANPC1 | |
| SCHEMBL17513905 | 0.80 | RAB9A (0.44) | MAPTHDAC1HDAC8ALDH1A1RAB9A | |
| SCHEMBL17513896 | 0.80 | CASP3 (0.46) | MAPTHPGDHDAC1HDAC2HDAC8 | |
| SCHEMBL17513938 | 0.78 | CA12 (0.39) | ATMMAPTFFAR1ALDH1A1TSHR | |
| SCHEMBL17513990 | 0.78 | FFAR1 (0.44) | MAPTFFAR1ALDH1A1TSHRRAB9A | |
| SCHEMBL14931632 | 0.76 | ATM (0.56) | ATMMAPTHPGDNPSR1HDAC1 | |
| SCHEMBL17513891 | 0.75 | CD38 (0.36) | MAPTALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3182992-A1 | METHODS OF TREATING MILD BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2017075535-A1 | METHODS OF TREATING NEURODEGENERATIVE CONDITIONS | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016028826-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |