Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513980 | 0.82 | ALDH1A1 (0.38) | S1PR4S1PR1S1PR3S1PR5HCAR2 | |
| SCHEMBL24660578 | 0.79 | TP53 (0.43) | HCAR2KMT2A | |
| Hydrochloric Acid SCHEMBL29463511 | 0.78 | TP53 (0.43) | HCAR2KMT2A | |
| Hydrochloric Acid SCHEMBL22637899 | 0.78 | TP53 (0.43) | HCAR2KMT2A | |
| SCHEMBL17514020 | 0.77 | SMN1; SMN2 (0.51) | S1PR1KMT2ACA1CA2CA9 | |
| SCHEMBL17513877 | 0.76 | TSHR (0.38) | TACR1MAPK14 | |
| SCHEMBL4248899 | 0.73 | SENP7 (0.37) | NR1H4KMT2A | |
| SCHEMBL17514015 | 0.71 | KMT2A (0.47) | KMT2A | |
| SCHEMBL12061519 | 0.70 | TACR1 (0.48) | TACR1SLC1A1CA1CA2CA7 | |
| SCHEMBL15875270 | 0.67 | L3MBTL1 (0.50) | NR1H4S1PR1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |