SCHEMBL176335

SCHEMBL176335

C=CC[SiH2]NC(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798528 0.72 ALDH1A1 (0.36) TGFBR1ALDH1A1
SCHEMBL28972965 0.67
SCHEMBL30604 0.67
Hydrochloric Acid SCHEMBL10610285 0.65 TSHR (0.45) TGFBR1ALDH1A1
SCHEMBL9348971 0.65
Ammonia Solution, Strong SCHEMBL9663785 0.65 TSHR (0.45) TGFBR1ALDH1A1
Ammonia Solution, Strong SCHEMBL1326687 0.65 TSHR (0.45) TGFBR1ALDH1A1
SCHEMBL5681532 0.64 TGFBR1 (0.38) TGFBR1ALDH1A1
Dimethylamine SCHEMBL3953015 0.64 TSHR (0.43) TGFBR1ALDH1A1
SCHEMBL2858627 0.64 ALDH1A1 (0.34) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384485-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS Wacker Chemie AG (DE) 2024-06-19 EP disclosed
WO-2024094292-A1 MULTI-STAGE COPOLYMERS AS BINDER FOR COATING AGENTS WACKER CHEMIE AG (DE) 2024-05-10 WO disclosed
WO-2023016627-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS WACKER CHEMIE AG (DE) 2023-02-16 WO disclosed
EP-2406328-B1 AQUEOUS SILANIZED SILICA DISPERSION NOURYON CHEMICALS INT BV (NL) 2020-05-06 EP disclosed
US-9187647-B2 Aqueous silanized silica dispersion AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-11-17 US disclosed
US-20140227515-A1 GAS BARRIER FILM MITSUI CHEMICALS TOHCELLO, INC. (JP) 2014-08-14 US disclosed
US-20120059089-A1 AQUEOUS SILANIZED SILICA DISPERSION AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-03-08 US disclosed
EP-2406328-A1 AQUEOUS SILANIZED SILICA DISPERSION Akzo Nobel Chemicals International B.V. (NL) 2012-01-18 EP disclosed
US-7981961-B2 Colloidal aqueous organopolysiloxane dispersions which contain binders and the use thereof WACKER CHEMIE AG (DE) 2011-07-19 US disclosed
US-20110009553-A1 COLLOIDAL AQUEOUS ORGANOPOLYSILOXANE DISPERSIONS WHICH CONTAIN BINDERS AND THE USE THEREOF WACKER CHEMIE AG (DE) 2011-01-13 US disclosed
US-7538153-B2 Compound of a powdery coating agent WACKER CHEMIE AG (DE) 2009-05-26 US disclosed
US-20070004859-A1 Priming agent for separating papers and films WACKER CHEMIE AG (DE) 2007-01-04 US disclosed
US-20060204703-A1 Use of silane-functional polyvinyl alcohols in priming agents for separating papers and films WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2006-09-14 US disclosed
US-20060194006-A1 Compound of a powdery coating agent WACKER CHEMIE AG (DE) 2006-08-31 US disclosed
EP-0414229-B1 Heat-sensitive recording material NEW OJI PAPER CO LTD (JP) 1994-08-03 EP disclosed
EP-0187673-B1 WATER RESISTANT COMPOSITION AND HEAT-SENSITIVE RECORDING SHEET CONTAINING THE SAME KURARAY CO., LTD. (JP) 1991-03-13 EP disclosed
EP-0123927-B1 WATER RESISTANT COMPOSITIONS KURARAY CO., LTD. (JP) 1990-07-25 EP disclosed
US-4708947-A POLYVINYL ALCOHOL, A CHITOSAN AND AN ALDEHYDE KURARAY CO., LTD. (JP) 1987-11-24 US disclosed
EP-0187673-A2 Water resistant composition and heat-sensitive recording sheet containing the same KURARAY CO., LTD. (JP) 1986-07-16 EP disclosed
US-4567221-A DEFOGGING AGENTS, SOLIDIFICATION OF SOILS KURARAY CO., LTD. (JP) 1986-01-28 US disclosed