SCHEMBL2858627

SCHEMBL2858627

C=CCCNC(=O)C(=C)C

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
TGFBR1 P36897 1/20 0.34
LMNA P02545 1/20 0.34
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
DDAH1 O94760 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
MAPT P10636 2/20 0.30
TSHR P16473 2/20 0.30
ABCC4 O15439 1/20 0.30
MAPK1 P28482 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL216867 0.94 TDP1 (0.36) ALDH1A1TGFBR1LMNAHRH4HRH3
SCHEMBL18133016 0.88 ALDH1A1 (0.40) ALDH1A1TGFBR1LMNAHRH4HRH3
SCHEMBL31208245 0.84 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2ZDHHC20ZDHHC2
SCHEMBL14813022 0.83 TGFBR1 (0.34) ALDH1A1TGFBR1SMN1; SMN2NPC1RAB9A
SCHEMBL316224 0.81 TGFBR1 (0.41) ALDH1A1TGFBR1SMN1; SMN2NPC1RAB9A
SCHEMBL273387 0.79
SCHEMBL23610103 0.78 DDAH1 (0.31) ALDH1A1LMNAHRH4HRH3DDAH1
SCHEMBL18579931 0.78 SMN1; SMN2 (0.35) ALDH1A1TGFBR1LMNASMN1; SMN2RAB9A
SCHEMBL30604 0.77
SCHEMBL24932476 0.77 ALDH1A1 (0.37) ALDH1A1LMNAHRH4HRH3DDAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559312-B1 REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS FOR METAL PRETREATMENT APPLICATIONS HENKEL AG & CO KGAA (DE) 2024-04-24 EP claimed
EP-3094695-B1 WATERBORNE COATING COMPOSITION WITH IMPROVED OPEN TIME ALLNEX NETHERLANDS BV (NL) 2018-10-24 EP claimed
EP-1715746-B1 CARD SHEET WITH STARCH COMPOSITIONS FORMING BREAKABLE LAYERS IN PRE-CUT SUBSTRATES AVERY DENNISON CORP (US) 2010-12-15 EP claimed
EP-1726604-B1 Acrylic modified alkyl hybrid latexes, coating composition, method of increasing and adjusting the viscosity and substrate coated EASTMAN CHEM CO (US) 2009-01-14 EP claimed
EP-1778804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS Arkema France (FR) 2007-05-02 EP claimed
WO-2006010804-A1 SINGLE-COMPONENT SYSTEM BASED ON CO-REACTIVE LATEX, PREPARATION METHOD AND USE IN THE FIELD OF FORMOL-FREE COATINGS ARKEMA FRANCE (FR) 2006-02-02 WO claimed
EP-1185567-B1 ACRYLIC MODIFIED WATERBORNE ALKYD OR URALKYD DISPERSIONS EASTMAN CHEM CO (US) 2005-01-12 EP claimed
EP-0875541-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2003-09-10 EP claimed
EP-0875540-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2002-11-13 EP claimed
EP-0927751-B1 Smear resistant pigmented ink jet inks containing Beta-diketone or ureido dispersants DU PONT (US) 2002-09-11 EP claimed
EP-0875540-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
EP-0875541-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
US-11787952-B2 Zwitterionic monomers, polyzwitterionic polymers formed therefrom, surface functionalization and surface modification ABF TECHNOLOGIES, LLC (US) 2023-10-17 US disclosed
US-11787952-B2 Zwitterionic monomers, polyzwitterionic polymers formed therefrom, surface functionalization and surface modification ABF TECHNOLOGIES, LLC (US) 2023-10-17 US disclosed
EP-3778526-B1 PLASTER PLATE SAINT GOBAIN PLACO (FR) 2022-05-11 EP disclosed
EP-3778526-A1 PLASTER PLATE SAINT-GOBAIN PLACO (FR) 2021-02-17 EP disclosed
EP-0875540-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2002-11-13 EP disclosed
WO-2001054896-A2 MULTILAYER COMPOSITE PRODUCT COMPRISING A PRESSURE-SENSITIVE AND TEMPERATURE-RESISTANT ADHESIVE POLYMER LAYER ATOFINA (FR) 2001-08-02 WO disclosed
EP-0875540-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP disclosed
EP-0875541-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP disclosed