Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822089 | 0.86 | ALDH1A1 (0.49) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL2823023 | 0.85 | CHRM2 (0.62) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL25818515 | 0.81 | ALDH1A1 (0.54) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL25818505 | 0.73 | ALDH1A1 (0.65) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL14747436 | 0.72 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL14564422 | 0.71 | CHRM2 (0.71) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL14288519 | 0.70 | CHRM2 (0.63) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL5905885 | 0.70 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL14564376 | 0.70 | CHRM2 (0.67) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL12656456 | 0.70 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3001199-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | Enzo Life Sciences, Inc. (US) | 2016-03-30 | — | — | EP | disclosed |