Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166733 | 0.85 | MEN1 (0.36) | INSRIGF1RALDH1A1TP53LMNA | |
| SCHEMBL15960820 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TP53LMNAKDM4EHTT | |
| SCHEMBL18801431 | 0.74 | ALOX5 (0.34) | INSRIGF1RESR1ESR2 | |
| SCHEMBL12703151 | 0.72 | GPR84 (0.30) | — | |
| SCHEMBL24895937 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL24106729 | 0.71 | ALDH1A1 (0.38) | INSRIGF1RALDH1A1TP53LMNA | |
| SCHEMBL22003200 | 0.71 | — | — | |
| SCHEMBL23099984 | 0.70 | MEN1 (0.40) | INSRIGF1RALDH1A1TP53LMNA | |
| SCHEMBL18828278 | 0.70 | — | — | |
| SCHEMBL19311818 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TP53LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2469341-B1 | Image bearing member and image forming method, image forming apparatus, and process cartridge | RICOH CO LTD (JP) | 2016-03-30 | — | — | EP | disclosed |