Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19311818 | 0.95 | ALDH1A1 (0.36) | ALDH1A1LMNATP53ESR1ESR2 | |
| SCHEMBL18400709 | 0.87 | NPSR1 (0.38) | ALDH1A1MEN1KMT2AHTTNPSR1 | |
| SCHEMBL20967930 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22784070 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2HTTNPSR1 | |
| SCHEMBL25894335 | 0.82 | PTGIR (0.36) | ALDH1A1LMNATP53HTTNPC1 | |
| SCHEMBL23099984 | 0.81 | MEN1 (0.40) | ALDH1A1LMNATP53ESR1ESR2 | |
| SCHEMBL24301563 | 0.80 | RELA (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23315073 | 0.80 | TRPM8 (0.31) | NPSR1 | |
| SCHEMBL19836373 | 0.80 | ALDH1A1 (0.33) | ALDH1A1NPSR1L3MBTL1KDM4ECYP3A4 | |
| SCHEMBL13709429 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNATP53ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387994-A1 | SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387994-A1 | SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION | MCCC2, CTRC, DDC | ALDH1A1 2438/4885LMNA 2073/4885TP53 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.