Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17636593 | 0.89 | ESR1 (0.34) | ALOX15ALDH1A1CYP2C9NR1I2LMNA | |
| SCHEMBL17636606 | 0.85 | ESR1 (0.41) | ALOX15ALDH1A1CYP2C9NR1I2LMNA | |
| SCHEMBL17636585 | 0.82 | ESR1 (0.58) | LMNAESR1ESR2MAPTSMN1; SMN2 | |
| SCHEMBL5429620 | 0.82 | ALDH1A1 (0.46) | ALOX15ALDH1A1CYP2C9NR1I2LMNA | |
| SCHEMBL17636601 | 0.80 | RORC (0.42) | ALOX15ALDH1A1HSD17B10ESR1ESR2 | |
| SCHEMBL31735188 | 0.79 | ALDH1A1 (0.43) | ALOX15ALDH1A1CYP2C9NR1I2LMNA | |
| SCHEMBL17636588 | 0.77 | ESR2 (0.48) | ALOX15CYP2C9LMNAESR1ESR2 | |
| SCHEMBL17636607 | 0.77 | NUDT1 (0.42) | LMNAESR1ESR2HSP90AA1NPSR1 | |
| SCHEMBL4063439 | 0.77 | ESR1 (0.61) | ALOX15ALDH1A1CYP2C9NR1I2LMNA | |
| SCHEMBL10453116 | 0.76 | ATM (0.45) | ALOX15ALDH1A1CYP2C9NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822237-B2 | Resin composition, film, polarizing plate protective film, polarizing plate, liquid crystal display device, and bis type alicyclic cardo phenol compound | FUJIFILM CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |